Professor of High-Throughput Chemical Biology, University of Edinburgh, Edinburgh, UK
Prof. Mark Bradley was awarded a First Class Honours degree in Chemistry from the University of Oxford in 1986. Remaining at Oxford, he completed a D.Phil. between 1986 and 1989, under the supervision of Professor Sir J.E. Baldwin FRS. He then moved to the USA, joining Professor C.T. Walsh at Harvard Medical School, Boston for a Lindemann Trust Postdoctoral Fellowship then a SERC/NATO Postdoctoral Fellowship. In 1991, he returned to the United Kingdom to take up a Royal Society Research Fellowship. He was at the University of Southampton from 1992–2004, initially as an independent Royal Society University Research Fellow (1992–1999), during which time he was awarded a personal chair in Combinatorial Chemistry (1997). During that time he led the Combinatorial Center of Excelent. In 2005 he took up his current position as Professor of High-Throughput Chemical Biology in Edinburgh. He won the Most Important Contribution to Solid Phase Chemistry award at the International Solid Phase and Combinatorial Technology Symposium, Edinburgh in September 1995 and has since received the GlaxoWellcome Award for Innovative Chemistry 1997, the Novartis Young Investigator of the Year 1998, the 1998 Zeneca Prize, the Pfizer Award in 1999 and a Novartis Lectureship in 2006. In 2008 he was elected Fellow of the Royal Society of Edinburgh. Professor Bradley is the European associate editor of the ACS Journal of Combinatorial Chemistry, a founder member of the European Society of Combinatorial Sciences and co-founder of the spin-out Ilika Technologies. His group has published over 200 articles in the form of papers, reviews and book chapters and filed over 15 PCT patents.
RESEARCH INTERESTS
The group is particularly interested in many aspects of High-Throughput and Combinatorial Chemistry technologies, with a clear biological outcome. A broad range of methodologies has been developed in the group, from polymer-microarrays, cellular carrier systems in the form of microspheres, peptoids and cellular penetrating peptides to PNA encoding libraries. One of the most exciting areas is the application of some of these technologies to both human and mouse stem cells thanks to the strong network of collaborators.
